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IgG versus IgM

Updated: Aug 28




"So what’s the difference between these two types of antibodies?"


"IgG antibodies make up the majority of immunoglobulins in the blood (70-89%), while IgM account for about 15%... Another main difference is that IgM antibodies are the first line of defense that B-cells create, while IgG antibodies are secreted after prolonged exposure to a harmful pathogen. IgG antibodies form the basis for long-term protection against specific pathogens, like the bacteria that can cause Lyme disease."


"In people with healthy immune systems, the Lyme disease IgM is normally detectable within a couple of weeks after infection, typically peaking around 4-6 weeks, then slowly declining over the next several months. The IgG begins around 4-6 weeks, peaking around 4-6 months, then slowly declining over the next several years."


"It does more than just initial protection, though. IgG antibodies are able to memorize certain pathogens after binding to them. Because of this, these antibodies give the immune system a recall ability."


"IgM antibodies are on the frontlines in the sense that they are produced first to provide fast but short-lived protection against illness."


"Evaluation of Patient IgM and IgG Reactivity Against Multiple Antigens for Improvement of Serodiagnostic Testing for Early Lyme Disease."


"What happens when everything adds up to a likely diagnosis of Lyme disease except the lab test results? It’s a question doctors face more often than many people realize."


"When a person comes in contact with an infectious agent, the body makes IgM antibodies as its first line of defense. In general, it takes two to four weeks to be at a consistently detectable level, with production peaking at around four weeks and becoming undetectable after six months."


"The second antibody produced in the body is IgG. It develops over four to eight weeks after exposure to BB, peaks at approximately six weeks and is gone in less than one year."


Lyme bands explained


Two videos to watch


Understanding Lyme results


Why Lyme Testing isn't always accurate

LYME TESTING POST


TESTING INFORMATION ON VARIOUS ISSUES


Disclaimer: Rise Above Lyme makes no claims about any possible benefit of using any product mentioned within this site. Always consult with your doctor before adding anything. The information shared is based on personal experience, years of accumulated researched resources from Lyme Literate doctors and polls conducted within Lyme groups from actual patient experience using these solution ideas.

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